Interphase review: Which event does NOT occur during interphase of the eukaryotic cell cycle?

Difficulty: Easy

Correct Answer: Chromatin condensation into visibly distinct chromosomes

Explanation:


Introduction / Context:
Interphase is the period of growth and preparation between divisions. It comprises G1, S, and G2 phases. Discriminating interphase events from mitotic events clarifies how cells prepare for accurate division.



Given Data / Assumptions:

  • Interphase includes intense biosynthesis and duplication of DNA and organelles.
  • Chromosome condensation into clearly visible structures is characteristic of prophase in M phase.
  • The question seeks the event that does not belong to interphase.


Concept / Approach:
During interphase, chromatin is generally decondensed (euchromatic) to permit transcription and replication. Visible, highly condensed chromosomes appear at the onset of mitosis. Thus, “chromatin condenses” (into classic X-shaped forms) is excluded from interphase.



Step-by-Step Solution:

List interphase processes: biomass accumulation, DNA synthesis (S phase), organelle duplication, checkpoint control.Contrast with mitosis: condensation, spindle formation, and chromosome segregation.Select the non-interphase event: chromatin condensation.


Verification / Alternative check:
Microscopy shows diffuse nuclei in interphase and distinct condensed chromosomes only during prophase to metaphase.



Why Other Options Are Wrong:

Protein synthesis: robust in G1/G2.Organelle replication: occurs to equip daughter cells.DNA replication: hallmark of S phase within interphase.Cyclin accumulation: interphase preparation for checkpoints.


Common Pitfalls:
Assuming visible chromosomes throughout the cycle; they are fully condensed only during mitosis, not interphase.



Final Answer:
Chromatin condensation into visibly distinct chromosomes.

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