Pharmaceuticals: which of the following is a drug used in oral contraceptive formulations (as an estrogen component)?

Difficulty: Easy

Correct Answer: Mestranol

Explanation:


Introduction:
Combined oral contraceptives typically contain an estrogen and a progestin. Recognizing common active ingredients is important for pharmacy, medicine, and biotechnology students.


Given Data / Assumptions:

  • Mestranol is a synthetic estrogen (a prodrug of ethinyl estradiol).
  • Other listed compounds have unrelated indications.
  • Question asks specifically for a contraceptive drug.


Concept / Approach:
Estrogen components (e.g., mestranol, ethinyl estradiol) are combined with progestins (e.g., norethindrone, levonorgestrel) to suppress ovulation and alter the endometrium/cervical mucus. Antibiotics (penicillin), analgesic/liniment component (methyl salicylate), and antibacterial sulfonamide (sulphadiazine) are not used as contraceptives.


Step-by-Step Solution:
Identify estrogenic agent: mestranol.Exclude antibiotics/analgesics: not contraceptives.Select mestranol as correct contraceptive component.


Verification / Alternative check:
Drug compendia list mestranol–norethindrone as a historical combination; modern products often use ethinyl estradiol instead of mestranol but the classification remains valid.


Why Other Options Are Wrong:

  • Penicillin: antimicrobial, no contraceptive effect.
  • Methyl salicylate: topical counterirritant.
  • Sulphadiazine: antibacterial sulfonamide.


Common Pitfalls:
Assuming any hormone-like name is a contraceptive; only specific estrogens/progestins are used for this indication.


Final Answer:
Mestranol

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