Taking option (c),
As sum of digits of 583 = 5 + 8 + 3 + = 16
and sum of digits of 488 = 4 + 8 + 8 = 20
Similarly, sum of digits of 293 + 2 + 9 + 3 = 14
and Sum of digits of 378 = 3 + 7 + 8 = 18
Here, difference of both are (20 - 16) = (18 - 14) = 4
∴ ? = 378